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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DYNC1H1
All Species:
29.7
Human Site:
S4370
Identified Species:
54.44
UniProt:
Q14204
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14204
NP_001367.2
4646
532408
S4370
K
T
R
T
D
S
T
S
D
G
R
P
A
W
M
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001112455
4147
474593
A3903
L
A
A
A
S
G
G
A
K
E
L
K
N
I
H
Dog
Lupus familis
XP_537556
4646
532374
S4370
K
A
R
T
D
S
T
S
D
G
R
P
A
W
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9JHU4
4644
532007
S4368
K
A
R
T
D
S
T
S
D
G
R
P
A
W
M
Rat
Rattus norvegicus
P38650
4644
532233
S4368
K
T
R
T
D
F
T
S
D
G
R
P
A
W
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512683
4644
532495
S4368
K
T
R
T
D
S
T
S
D
G
R
P
A
W
M
Chicken
Gallus gallus
XP_421371
4617
529846
S4341
K
T
R
T
D
S
T
S
D
G
R
P
A
W
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001036210
4643
533172
S4368
K
Q
R
S
T
S
S
S
D
A
Q
P
A
W
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P37276
4639
530166
E4360
Q
S
A
V
G
R
G
E
D
G
R
P
S
W
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19020
4568
521560
G4318
P
Q
W
M
A
Q
L
G
E
L
A
K
Q
W
L
Sea Urchin
Strong. purpuratus
XP_797645
4652
531803
S4369
Q
E
I
A
R
H
S
S
D
G
R
P
A
W
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P36022
4092
471329
S3849
Q
N
I
Q
M
S
L
S
W
V
K
T
Y
L
H
Red Bread Mold
Neurospora crassa
P45443
4367
495560
E4123
F
R
L
F
L
S
M
E
S
S
P
K
I
P
V
Conservation
Percent
Protein Identity:
100
N.A.
83.9
99.2
N.A.
99
98.5
N.A.
98.4
95.5
N.A.
90.9
N.A.
71.9
N.A.
55.6
74.5
Protein Similarity:
100
N.A.
84.5
99.6
N.A.
99.4
99.2
N.A.
99.4
97.1
N.A.
95.8
N.A.
85.2
N.A.
73.3
86.2
P-Site Identity:
100
N.A.
0
93.3
N.A.
93.3
93.3
N.A.
100
100
N.A.
60
N.A.
40
N.A.
6.6
53.3
P-Site Similarity:
100
N.A.
6.6
93.3
N.A.
93.3
93.3
N.A.
100
100
N.A.
80
N.A.
60
N.A.
20
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.8
49.8
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.9
67.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
24
16
16
8
0
0
8
0
8
8
0
62
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
47
0
0
0
70
0
0
0
0
0
0
% D
% Glu:
0
8
0
0
0
0
0
16
8
8
0
0
0
0
0
% E
% Phe:
8
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
8
16
8
0
62
0
0
0
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
16
% H
% Ile:
0
0
16
0
0
0
0
0
0
0
0
0
8
8
0
% I
% Lys:
54
0
0
0
0
0
0
0
8
0
8
24
0
0
0
% K
% Leu:
8
0
8
0
8
0
16
0
0
8
8
0
0
8
8
% L
% Met:
0
0
0
8
8
0
8
0
0
0
0
0
0
0
70
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
8
70
0
8
0
% P
% Gln:
24
16
0
8
0
8
0
0
0
0
8
0
8
0
0
% Q
% Arg:
0
8
54
0
8
8
0
0
0
0
62
0
0
0
0
% R
% Ser:
0
8
0
8
8
62
16
70
8
8
0
0
8
0
0
% S
% Thr:
0
31
0
47
8
0
47
0
0
0
0
8
0
0
0
% T
% Val:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
8
% V
% Trp:
0
0
8
0
0
0
0
0
8
0
0
0
0
77
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _